Article
k mdiff, large-scale and user-friendly differential k-mer analyses.
Bioinformatics (Oxford, England) - 13 Dec 2022
Lemane Téo, Chikhi Rayan, Peterlongo Pierre
Abstract excerpt
SUMMARY: Genome wide association studies elucidate links between genotypes and phenotypes. Recent studies point out the interest of conducting such experiments using k-mers as the base signal instead of single-nucleotide polymorphisms. We propose a tool, kmdiff, that performs differential k-mer analyses on large sequencing cohorts in an order of magnitude less time and memory than previously possible....
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