Article

2-kupl: mapping-free variant detection from DNA-seq data of matched samples

2021-01-19

Abstract excerpt

The detection of genome variants, including point mutations, indels and structural variants, is a fundamental and challenging computational problem. We address here the problem of variant detection between two deep-sequencing (DNA-seq) samples, such as two human samples from an individual patient, or two samples from distinct bacterial strains. The preferred strategy in such a case is to align each sample to a com...

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Literature Corpus work: 20cd3efe-e8e9-53ed-b4fb-ea323a6e149f
DOI: 10.1101/2021.01.17.427048

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