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Article

Significant Contribution of Interleukin-18 Genotypes to Childhood Acute Lymphocytic Leukemia Risk in Taiwanese.

Anticancer research - 1 Nov 2022

Chen Chao-Chun, Tzeng Huey-En, Kuo Chien-Chung, Lim S Ngern Sae, Hsu Pei-Chen, Hsu Yuan-Nian, Chin Yu-Ting, Chang Wen-Shin, Wang Chung-Hsing, Tsai Chia-Wen, Pei Jen-Sheng, Bau DA-Tian

Abstract excerpt

BACKGROUND/AIM: Evidence has shown that interleukin-18 (IL-18) has both antitumor and pro-tumor effects in various types of leukemia. The current study aimed at investigating the contribution of IL-18 polymorphisms to the risk of childhood acute lymphocytic leukemia (ALL) in Taiwan. MATERIALS AND METHODS: IL-18 promoter -656 (rs1946519), -607 (rs1946518), and -137 (rs187238) genotypes of 266 childhood ALL cases...

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Source

Identifiers

PMID: 36288881
DOI: 10.21873/anticanres.16035

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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