Article
Contribution of Matrix Metalloproteinase-7 Genotypes to the Risk of Non-solid Tumor, Childhood Leukemia.
Anticancer research - 1 Dec 2017
Pei Jen-Sheng, Chou An-Kuo, Hsu Pei-Chen, Tsai Chia-Wen, Chang Wen-Shin, Wu Meng-Feng, Wu Ming-Hsien, Hsia Te-Chun, Cheng Shun-Ping, Bau DA-Tian
Abstract excerpt
BACKGROUND/AIM: The matrix metalloproteinases (MMPs) are important in inflammation and carcinogenesis, and the genotypic role of MMP7 has never been examined in leukemia to date. Therefore, in this study we aimed to evaluate the contribution of the genotypic variants in the promoter region of MMP7 (A-181G and C-153T) to childhood acute lymphoblastic leukemia (ALL) risk in Taiwan. MATERIALS AND METHODS: In this...
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