Article
Significant Contribution of Interleukin-18 Genotypes to Lung Cancer Risk in Taiwanese.
Anticancer research - 1 Jul 2022
Wu Meng-Feng, Chen Li-Hsiou, Hsia Ning-Yi, Shen Yi-Cheng, Shen Te-Chun, Wang Zhi-Hong, Yang Ya-Chen, Wang Yun-Chi, Chang Wen-Shin, Hsia Te-Chun, Bau DA-Tian, Tsai Chia-Wen
Abstract excerpt
BACKGROUND/AIM: The elevated expression of interleukin-18 (IL-18) among lung cancer patients raised our curiosity to examine the role of IL-18 genotypes in lung cancer. MATERIALS AND METHODS: IL-18 -656 (rs1946519), -607 (rs1946518), and -137 (rs187238) genotypes of 358 lung cancer cases and 716 controls were determined via the PCR-RFLP methodology. RESULTS: The distributions of genotypic and allelic frequencies...
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