IL-10 gene polymorphism and influence of chemotherapy on cytokine plasma levels in childhood acute lymphoblastic leukemia patients: IL-10 polymorphism and plasma levels in leukemia patients.

doi:10.1016/j.bcmd.2015.06.004

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IL-10 gene polymorphism and influence of chemotherapy on cytokine plasma levels in childhood acute lymphoblastic leukemia patients: IL-10 polymorphism and plasma levels in leukemia patients.

Blood cells, molecules & diseases - 1 Aug 2015

Hiroki Carlos Hiroji, Amarante Marla Karine, Petenuci Diego Lima, Sakaguchi Alberto Yoichi, Trigo Fausto Celso, Watanabe Maria Angelica Ehara, de Oliveira Carlos Eduardo Coral

Abstract excerpt

Acute Lymphoblastic Leukemia is the leading form of cancer in infancy, and compelling evidences suggest an involvement of altered immune competence on this malignancy pathogenesis. Interleukin 10 (IL-10) is a pleiotropic cytokine designated as an immunosuppressive molecule, but may act as an immunostimulant factor in cancer development and progression. An IL-10 single nucleotide polymorphism (SNP) rs1800896 has...

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PMID: 26142334
DOI: 10.1016/j.bcmd.2015.06.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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