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Article

The -137G/C Polymorphism in Interleukin-18 Gene Promoter Contributes to Chronic Lymphocytic and Chronic Myelogenous Leukemia Risk in Turkish Patients.

Turkish journal of haematology : official journal of Turkish Society of Haematology - 1 Dec 2015

Yalçın Serap, Mutlu Pelin, Çetin Türker, Sarper Meral, Özgür Gökhan, Avcu Ferit

Abstract excerpt

OBJECTIVE: Interleukin-18 (IL-18) is a cytokine that belongs to the IL-1 superfamily and is secreted by various immune and nonimmune cells. Evidence has shown that IL-18 has both anticancer and procancer effects. The aim of this study was to evaluate the relationship between IL-18 gene polymorphisms and susceptibility to chronic lymphocytic leukemias (CLL) and chronic myelogenous leukemias (CML) in Turkish...

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Source

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Identifiers

PMID: 26376814
DOI: 10.4274/tjh.2014.0126
PMCID: PMC4805319

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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