Article
MiR-196a-2 Genotypes Determine the Susceptibility and Early Onset of Childhood Acute Lymphoblastic Leukemia.
Anticancer research - 1 Aug 2020
Chen Chao-Chun, Hsu Pei-Chen, Shih Liang-Chun, Hsu Yuan-Nian, Kuo Chien-Chung, Chao Che-Yi, Chang Wen-Shin, Tsai Chia-Wen, Bau DA-Tian, Pei Jen-Sheng
Abstract excerpt
BACKGROUND/AIM: The roles of microRNAs (miRNAs) in tumorigenesis have attracted a lot of attention. The current study aimed at examining the association of the miR-196a-2 rs11614913 genotypes with susceptibility to childhood acute lymphoblastic leukemia (ALL) in Taiwan. MATERIALS AND METHODS: This case-control investigation recruited 266 patients with childhood ALL and 266 healthy controls, and the miR-196a-2...
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