Article
A large genome-wide association study of QT interval length utilizing electronic health records.
Genetics - 30 Nov 2022
Hoffmann Thomas J, Lu Meng, Oni-Orisan Akinyemi, Lee Catherine, Risch Neil, Iribarren Carlos
Abstract excerpt
QT interval length is an important risk factor for adverse cardiovascular outcomes; however, the genetic architecture of QT interval remains incompletely understood. We conducted a genome-wide association study of 76,995 ancestrally diverse Kaiser Permanente Northern California members enrolled in the Genetic Epidemiology Research on Adult Health and Aging cohort using 448,517 longitudinal QT interval...
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