Article
Genetic Basis and Prognostic Value of Exercise QT Dynamics.
Circulation. Genomic and precision medicine - 1 Aug 2020
van Duijvenboden Stefan, Ramírez Julia, Young William J, Mifsud Borbala, Orini Michele, Tinker Andrew, Munroe Patricia B, Lambiase Pier D
Abstract excerpt
BACKGROUND: Abnormal QT interval responses to heart rate (QT dynamics) is an independent risk predictor for cardiovascular disease in patients, but its genetic basis and prognostic value in a population-based cohort have not been investigated. METHODS: QT dynamics during exercise and recovery were derived in 56 643 individuals from UK Biobank without a history of cardiovascular events. Genome-wide association...
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