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Article

Genomic and pleiotropic analyses of resting QT interval identifies novel loci and overlap with atrial electrical disorders.

Human molecular genetics - 30 Nov 2021

van Duijvenboden Stefan, Ramírez Julia, Young William J, Orini Michele, Mifsud Borbala, Tinker Andrew, Lambiase Pier D, Munroe Patricia B

Abstract excerpt

The resting QT interval, an electrocardiographic (ECG) measure of ventricular myocardial repolarization, is a heritable risk marker of cardiovascular mortality, but the mechanisms remain incompletely understood. Previously reported candidate genes have provided insights into the regulatory mechanisms of the QT interval. However, there are still important knowledge gaps. We aimed to gain new insights by (i)...

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PMID: 34274964
DOI: 10.1093/hmg/ddab197
PMCID: PMC8643508

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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