Article
Prime Editing: An Emerging Tool in Cancer Treatment.
Molecular biotechnology - 1 Apr 2023
Sen Debmitra, Sarkar Sutripta, Mukhopadhyay Poulami
Abstract excerpt
Prime Editing is a CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) based genome editing technique having promising potential in terms of reducing off target activity. It introduces fragments of DNA sequences into the target site using a guide RNA (gRNA) molecule, composed of both the sequence that is to be inserted into the target site along with an inactive Cas9 nickase and a reverse...
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