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The Advancement and Applications of Prime Editing

2024-11-22

Abstract excerpt

Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR), an exceptionally potent genome-editing technique developed in 2012, is the ideal tool of the future for treating diseases by permanently correcting deleterious base mutations or disrupting disease-causing genes with great precision and efficiency. However, it is prone to cleaving double-stranded DNA in off-target genes and generating random mutati...

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Literature Corpus work
3a18e972-d33a-5abd-8a8f-ad6efe2f835f
DOI
10.20944/preprints202411.1633.v1
Open publication

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The Advancement and Applications of Prime EditingDOI 10.20944/preprints202411.1633.v1
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