Article
Introduction of mutations in plants with prime editing.
Methods (San Diego, Calif.) - 1 Oct 2021
Hao Lijun, Pu Xiangdong, Song Jingyuan
Abstract excerpt
The emergence of a clustered regularly interspaced short palindromic repeats/CRISPR-associated proteins (CRISPR/Cas) system has had a revolutionary impact on plant biology. However, this system and further developed base editing are limited by their inherent imperfection. Prime editing, a just arrival technology based on CRISPR/Cas, can directly and precisely edit a specified DNA site without double strand breaks...
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