Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prime editing in hematopoietic stem cells—From ex vivo to in vivo CRISPR-based treatment of blood disorders

10 Mar 2023

Abstract excerpt

Prime editing of human hematopoietic stem cells has the potential to become a safe and efficient way of treating diseases of the blood directly in patients. By allowing site-targeted gene intervention without homology-directed repair donor templates and DNA double-stranded breaks, the invention of prime editing fuels the exploration of alternatives to conventional recombination-based ex vivo genome editing of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CRISPR and Genetic Engineering
Share to Cytomegalovirus and herpesvirus research
Share to Mosquito-borne diseases and control

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36969373
DOI: 10.3389/fgeed.2023.1148650

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prime editing in hematopoietic stem cells—From ex vivo to in vivo CRISPR-based treatment of blood disordersPMID 36969373Read ↗

Genome Editing Therapy for the Blood: Ex Vivo Success and In Vivo ProspectsSemantic proximity Read ↗

In Vivo Hematopoietic Stem Cell Genome Editing: Perspectives and LimitationsSemantic proximity Read ↗

Near-perfect precise on-target editing of human hematopoietic stem and progenitor cellsSemantic proximity Read ↗

Near-perfect precise on-target editing of human hematopoietic stem and progenitor cellsSemantic proximity Read ↗

Improved nuclease-based prime editing by DNA repair modulation and pegRNA engineeringSemantic proximity Read ↗

The changing landscape of gene editing in hematopoietic stem cells: a step towards Cas9 clinical translationSemantic proximity Read ↗

Prime Editing: An Emerging Tool in Cancer Treatment.Semantic proximity Read ↗

Prime Editing for Human Gene Therapy: Where Are We Now?Semantic proximity Read ↗

Therapy Development by Genome Editing of Hematopoietic Stem CellsSemantic proximity Read ↗

CRISPR medicine for blood disorders: Progress and challenges in deliverySemantic proximity Read ↗

CRISPR to fix bad blood: a new tool in basic and clinical hematologySemantic proximity Read ↗

A Curative DNA Code for Hematopoietic DefectsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.