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Article

Genomic Landscape of Mixed-Phenotype Acute Leukemia.

International journal of molecular sciences - 24 Sept 2022

Hennawi Marah, Pakasticali Nagehan, Tashkandi Hammad, Hussaini Mohammad

Abstract excerpt

Mixed-phenotype leukemia (MPAL) is a type of acute leukemia in which the blast population shows mixed features of myeloid, T-lymphoid, and/or B-lymphoid differentiation. MPALs are rare and carry a poor prognosis, thus, often pose both a diagnostic and therapeutic challenge. Conventionally, the diagnosis of MPAL requires either a single blast population with a lineage-defining phenotypic expression of multiple...

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Identifiers

PMID: 36232559
DOI: 10.3390/ijms231911259
PMCID: PMC9569865

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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