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Article

An update on classification, genetics, and clinical approach to mixed phenotype acute leukemia (MPAL).

Annals of hematology - 1 Jun 2018

Khan Maliha, Siddiqi Rabbia, Naqvi Kiran

Abstract excerpt

Mixed phenotype acute leukemia (MPAL) is an uncommon diagnosis, representing only about 2-5% of acute leukemia cases. The blast cells of MPAL express multilineage immunophenotypic markers and may have a shared B/T/myeloid phenotype. Due to historical ambiguity in the diagnosis of MPAL, the genetics and clinical features of this disease remain poorly characterized. Based on the 2008 and 2016 World Health...

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PMID: 29546454
DOI: 10.1007/s00277-018-3297-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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