Article
Mixed-phenotype acute leukemia: state-of-the-art of the diagnosis, classification and treatment.
Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia - 1 Sept 2017
Cernan Martin, Szotkowski Tomas, Pikalova Zuzana
Abstract excerpt
Mixed-phenotype acute leukemia (MPAL) is a heterogeneous group of hematopoietic malignancies in which blasts show markers of multiple developmental lineages and cannot be clearly classified as acute myeloid or lymphoblastic leukemias. Historically, various names and classifications were used for this rare entity accounting for 2-5% of all acute leukemias depending on the diagnostic criterias used. The currently...
Topics
- Hematopoietic Stem Cell Transplantation
- Humans
- Immunophenotyping
- Leukemia, Biphenotypic, Acute
- Leukemia, Myeloid, Acute
- Phenotype
- Precursor Cell Lymphoblastic Leukemia-Lymphoma
- Prognosis
- World Health Organization