Article
Defining 2 biologically and clinically distinct groups in acute leukemia with a mixed phenotype
15 Jan 2025
Abstract excerpt
ABSTRACT: A mixed phenotype (MP) is a characteristic of de novo MP acute leukemia (MPAL), but it can also be found in other leukemias. It poses substantial classification and management dilemmas. Herein, we report a large cohort of acute leukemia with MP and define acute myeloid leukemia with MP (AML-MP) and MPAL as 2 distinct groups by characterizing clinical, genetic, and transcriptomic features. Clinically,...
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