Article
Mixed-phenotype acute leukemia: current challenges in diagnosis and therapy.
Current opinion in hematology - 1 Mar 2017
Wolach Ofir, Stone Richard M
Abstract excerpt
PURPOSE OF REVIEW: Mixed-phenotype acute leukemia (MPAL) is a rare disease that poses many diagnostic and therapeutic challenges. Patients with MPAL are considered to have poor outcomes. The difficulties in classifying this leukemia, the lack of prospectively collected data concerning therapeutic outcomes, and rare incidence result in much uncertainty as to the best approach for patients with MPAL. RECENT...
Topics
- Biomarkers, Tumor
- Combined Modality Therapy
- Genetic Variation
- Hematopoietic Stem Cell Transplantation
- Humans
- Immunophenotyping
- Leukemia, Biphenotypic, Acute
- Remission Induction
- Transplantation, Homologous
- Treatment Outcome