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Mixed-Phenotype Acute Leukemia: Clinical Diagnosis and Therapeutic Strategies

15 Aug 2022

Abstract excerpt

Mixed-phenotype acute leukemia (MPAL) comprises a heterogenous group of leukemias that are genetically, immunophenotypically, and clinically, diverse. Given the rarity of the disease, the diagnosis and treatment of MPAL is extremely challenging. Recent collaborative efforts have made significant progress in understanding the complex genomic landscape of MPAL. Some retrospective studies support starting ALL-type...

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PMID: 36009521
DOI: 10.3390/biomedicines10081974

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