Article
Combined Cellular Thermometry Reveals That Salmonella typhimurium Warms Macrophages by Inducing a Pyroptosis-like Phenotype.
Journal of the American Chemical Society - 26 Oct 2022
Wu Leyang, Chen Feng, Chang Xiaoyao, Li Lin, Yin Xingpeng, Li Can, Wang Fangxu, Li Chenyang, Xu Qin, Zhuang Hongqin, Gu Ning, Hua Zi-Chun
Abstract excerpt
The attenuated Salmonella typhimurium VNP20009, enriched in tumors, is known to have antitumor effects and recruit macrophages. Little is known, however, about whether VNP will lead to specific changes in macrophages, e.g., cell temperature. Here, using a real-time wireless multicell thermometry system, we reported for the first time that VNP20009 increases the macrophage temperature by 0.2 °C. Nigericin,...
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