Article
Fever-Range Hyperthermia Promotes Macrophage Polarization towards Regulatory Phenotype M2b.
International journal of molecular sciences - 17 Dec 2023
Kozłowski Henryk Mikołaj, Sobocińska Justyna, Jędrzejewski Tomasz, Maciejewski Bartosz, Dzialuk Artur, Wrotek Sylwia
Abstract excerpt
Fever-range hyperthermia (FRH) is utilized in chronic disease treatment and serves as a model for fever's thermal component investigation. Macrophages, highly susceptible to heat, play a pivotal role in various functions determined by their polarization state. However, it is not well recognized whether this process can be modulated by FRH. To address this, we used two different macrophage cell lines that were...
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