Article
The interplay between Salmonella typhimurium and its macrophage host--what can it teach us about innate immunity?
Immunology letters - 22 Jan 2003
Linehan Sheena A, Holden David W
Abstract excerpt
Salmonella enterica sv. Typhimurium (S. typhimurium) is a genetically tractable, facultative intracellular pathogen, whose capacity to cause systemic disease in mice depends upon its ability to survive and replicate within macrophages. The identification of Salmonella mutants that lack this activity, has provided a tool with which to dissect the mechanisms used by Salmonella to establish a permissive niche, and...
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