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Article

Associations of polygenic risks, depression, and obesity-related traits in Taiwan Biobank.

Journal of affective disorders - 1 Jan 2023

Liao Shu-Fen, Su Chun-Yun, Su Mei-Hsin, Chen Cheng-Yun, Chen Chia-Yen, Lin Yen-Feng, Pan Yi-Jiun, Hsiao Po-Chang, Chen Pei-Chun, Huang Yen-Tsung, Wu Chi-Shin, Wang Shi-Heng

Abstract excerpt

BACKGROUND: The comorbidity of obesity and major depressive disorder (MDD) may be attributable to a bidirectional relationship and shared genetic influence. We aimed to examine the polygenic associations between obesity and MDD and to characterize their corresponding impacts on the obesity mechanism. METHODS: Genome-wide genotyping was available in 106,604 unrelated individuals from Taiwan Biobank. Polygenic risk...

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Identifiers

PMID: 36206878
DOI: 10.1016/j.jad.2022.09.149

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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