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Article

Association Between Body Mass Index and Depression/Anxiety in an East Asian Population: A Mendelian Randomization Study.

The Kaohsiung journal of medical sciences - 1 Jul 2026

Lee Perl Han, Chen Szu-Chia, Lee Chien-Hung, Geng Jiun-Hung, Ko Chih-Hung

Abstract excerpt

Obesity and psychiatric disorders are the leading causes of global morbidity. Epidemiological studies suggest a bidirectional link between higher body mass index (BMI) and mental health outcomes, but the direction of causality remains uncertain due to confounding and reverse causation. We performed a Mendelian randomization (MR) analysis using genetic instruments for BMI (13 and 17 single-nucleotide polymorphisms...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41439371
DOI: 10.1002/kjm2.70161
PMCID: PMC13344266

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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