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Article

In vivo stress reporters as early biomarkers of the cellular changes associated with progeria.

Journal of cellular and molecular medicine - 1 Nov 2022

Inesta-Vaquera Francisco, Weiland Florian, Henderson Colin J, Wolf Charles Roland

Abstract excerpt

Age-related diseases account for a high proportion of the total global burden of disease. Despite recent advances in understanding their molecular basis, there is a lack of suitable early biomarkers to test selected compounds and accelerate their translation to clinical trials. We have investigated the utility of in vivo stress reporter systems as surrogate early biomarkers of the degenerative disease...

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Identifiers

PMID: 36201626
DOI: 10.1111/jcmm.17574
PMCID: PMC9639039

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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