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Hutchinson-Gilford Progeria Syndrome: A Literature Review

31 Aug 2022

Abstract excerpt

Hutchinson-Gilford progeria syndrome (HGPS) is a premature aging condition that involves genetic mutations, resulting in debilitating phenotypic features. The present state of knowledge on the molecular pathways that contribute to the pathophysiology of HGPS and the techniques being tested in vitro and in vivo to combat progerin toxicity have been discussed here. Nuclear morphological abnormalities, dysregulated...

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PMID: 36196312
DOI: 10.7759/cureus.28629

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