Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Werner and Hutchinson-Gilford progeria syndromes: mechanistic basis of human progeroid diseases.

Nature reviews. Molecular cell biology - 1 May 2007

Kudlow Brian A, Kennedy Brian K, Monnat Raymond J

Abstract excerpt

Progeroid syndromes have been the focus of intense research in part because they might provide a window into the pathology of normal ageing. Werner syndrome and Hutchinson-Gilford progeria syndrome are two of the best characterized human progeroid diseases. Mutated genes that are associated with these syndromes have been identified, mouse models of disease have been developed, and molecular studies have...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Damage
Share to Exodeoxyribonucleases
Share to Lamin Type A

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Progeria

Share to Protein Processing, Post-Translational

Share to RecQ Helicases

Share to Werner Syndrome

Share to Werner Syndrome Helicase

Source

Identifiers

PMID: 17450177
DOI: 10.1038/nrm2161

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Werner and Hutchinson-Gilford progeria syndromes: mechanistic basis of human progeroid diseases.PMID 17450177Read ↗

Hutchinson-Gilford Progeria Syndrome: A Literature ReviewSemantic proximity Read ↗

Progeria: a rare genetic premature ageing disorder.Semantic proximity Read ↗

What can progeroid syndromes tell us about human aging?Semantic proximity Read ↗

Prematurely aged children: molecular alterations leading to Hutchinson-Gilford progeria and Werner syndromes.Semantic proximity Read ↗

Premature aging disorders: A clinical and genetic compendium.Semantic proximity Read ↗

Hutchinson-Gilford Progeria Syndrome—Current Status and Prospects for Gene Therapy TreatmentSemantic proximity Read ↗

Premature aging syndromes: From patients to mechanism.Semantic proximity Read ↗

Model of human aging: recent findings on Werner's and Hutchinson-Gilford progeria syndromes.Semantic proximity Read ↗

Hutchinson-Gilford Progeria Syndrome: A Premature Aging Disease.Semantic proximity Read ↗

Genetics of aging, progeria and lamin disorders.Semantic proximity Read ↗

Human aging and progeria.Semantic proximity Read ↗

Towards delineating the chain of events that cause premature senescence in the accelerated aging syndrome Hutchinson-Gilford progeria (HGPS).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.