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Article

TGF-β in developmental and fibrogenic EMTs

29 Sept 2022

Abstract excerpt

TGF-β plays a prominent role as an inducer of epithelial-mesenchymal transitions (EMTs) during development and wound healing and in disease conditions such as fibrosis and cancer. During these processes EMT occurs together with changes in cell proliferation, differentiation, communication, and extracellular matrix remodeling that are orchestrated by multiple signaling inputs besides TGF-β. Chief among these...

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PMID: 36183999
DOI: 10.1016/j.semcancer.2022.09.004

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