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Article

Interrogation of TERT promoter hotspot mutations in ameloblastoma and ameloblastic carcinoma.

Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Mar 2023

Magalhães Maria Carolina Silva Versieux, Felix Fernanda Aragão, Guimarães Letícia Martins, Dos Santos Jean Nunes, de Marco Luiz Armando, Gomez Ricardo Santiago, Gomes Carolina Cavaliéri, de Sousa Sílvia Ferreira

Abstract excerpt

BACKGROUND: TERT promoter mutations increase telomerase activity, conferring cell immortality. The coexistence of TERT promoter mutations with BRAFV600E is associated with aggressiveness. Ameloblastoma and ameloblastic carcinoma are infiltrative neoplasms that harbor BRAFV600E; however, it remains unknown if these odontogenic tumors also show TERT promoter mutations. METHODS: Genomic DNA of paraffin-embedded...

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PMID: 36169975
DOI: 10.1111/jop.13364

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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