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Article

Craniopharyngiomas, including Recurrent Cases, Lack TERT Promoter Hotspot Mutations.

Neurologia medico-chirurgica - 15 Jun 2021

Fujio Shingo, Juratli Tareq A, Takajo Tomoko, Arita Kazunori, Nagano Yushi, Yoshimoto Koji, Nayyar Naema, Curry William T, Martinez-Lage Maria, Cahill Daniel P, Barker Fred G, Brastianos Priscilla K

Abstract excerpt

Adamantinomatous craniopharyngiomas (ACP) are characterized by alterations in the CTNNB1 gene while almost all papillary craniopharyngiomas (PCP) harbor a canonical V600E mutation in the BRAF gene. Although other recurrent driver genes have not been described to date in craniopharyngiomas, the heterogeneous clinical course of these tumors might be associated with the acquisition of further genomic alterations. It...

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Identifiers

PMID: 33967180
DOI: 10.2176/nmc.rc.2020-0339
PMCID: PMC8258007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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