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Molecular evaluation of gene mutation profiles and copy number variations in pediatric acute myeloid leukemia.

Leukemia research - 1 Nov 2022

Meena Jagdish Prasad, Pathak Nivedita, Gupta Aditya Kumar, Bakhshi Sameer, Gupta Ritu, Makkar Harshita, Seth Rachna

Abstract excerpt

BACKGROUND: The objectives of this study were to investigate the mutation profiles of targeted genes and copy number variations (CNVs) in normal cytogenetics (CN) pediatric acute myeloid leukemia (AML). METHODS: This prospective study was conducted from October 2018 to December 2020. The next-generation sequencing (NGS) and chromosomal microarray analyses (CMA) were performed in pediatric CN-AML patients....

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PMID: 36162216
DOI: 10.1016/j.leukres.2022.106954

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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