Article
LncRNA PSR Regulates Vascular Remodeling Through Encoding a Novel Protein Arteridin.
Circulation research - 14 Oct 2022
Yu Junyi, Wang Wei, Yang Jining, Zhang Ye, Gong Xue, Luo Hao, Cao Nian, Xu Zaicheng, Tian Miao, Yang Peili, Mei Qiao, Chen Zhi, Li Zhuxin, Li Chuanwei, Duan Xudong, Lyu Qing Rex, Gao Chen, Zhang Bing, Wang Yibin, Wu Gengze, Zeng Chunyu
Abstract excerpt
RATIONALE: Vascular smooth muscle cells (VSMCs) phenotype switch from contractile to proliferative phenotype is a pathological hallmark in various cardiovascular diseases. Recently, a subset of long noncoding RNAs was identified to produce functional polypeptides. However, the functional impact and regulatory mechanisms of long noncoding RNAs in VSMCs phenotype switching remain to be fully elucidated. OBJECTIVES:...
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