Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Melanoma differentiation associated gene‐9/syndecan binding protein promotes hepatocellular carcinoma

19 Sept 2022

Abstract excerpt

BACKGROUND AND AIMS: The oncogene Melanoma differentiation associated gene-9/syndecan binding protein (MDA-9/SDCBP) is overexpressed in many cancers, promoting aggressive, metastatic disease. However, the role of MDA-9 in regulating hepatocellular carcinoma (HCC) has not been well studied. APPROACH AND RESULTS: To unravel the function of MDA-9 in HCC, we generated and characterized a transgenic mouse with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer, Hypoxia, and Metabolism
Share to Proteoglycans and glycosaminoglycans research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36120720
DOI: 10.1002/hep.32797

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Melanoma differentiation associated gene‐9/syndecan binding protein promotes hepatocellular carcinomaPMID 36120720Read ↗

Knockout of MDA-9/Syntenin (SDCBP) expression in the microenvironment dampens tumor-supporting inflammation and inhibits melanoma metastasis.Semantic proximity Read ↗

SOX9 is a critical regulator of TSPAN8-mediated metastasis in pancreatic cancerSemantic proximity Read ↗

Molecular mechanisms of IL-33–mediated stromal interactions in cancer metastasisSemantic proximity Read ↗

CRISPR-Cas9 Knockdown and Induced Expression of CD133 Reveal Essential Roles in Melanoma Invasion and MetastasisSemantic proximity Read ↗

BRAF inhibition increases TGFβ2 production and stimulates metastasis in mice with endogenous BRAFV600E-induced hepatocellular carcinoma.Semantic proximity Read ↗

Functional identification of distinct sets of antitumor activities mediated by the FKBP gene familySemantic proximity Read ↗

SOX9 is a dose-dependent metastatic fate determinant in melanomaSemantic proximity Read ↗

Tetraspanin CD9 promotes the invasive phenotype of human fibrosarcoma cells via upregulation of matrix metalloproteinase-9.Semantic proximity Read ↗

A negative feedback loop between KLF9 and the EMT program dictates metastasis of hepatocellular carcinomaSemantic proximity Read ↗

Cross-species analysis reveals unique and shared roles of Sox9 and Sox10 (SOXE family) transcription factors in melanomaSemantic proximity Read ↗

Liver-specific overexpression of matrix metalloproteinase 9 (MMP-9) in transgenic mice accelerates development of hepatocellular carcinoma.Semantic proximity Read ↗

Transcriptional regulator CTR9 promotes hepatocellular carcinoma progression and metastasis via increasing PEG10 transcriptional activitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.