Article
Knockout of MDA-9/Syntenin (SDCBP) expression in the microenvironment dampens tumor-supporting inflammation and inhibits melanoma metastasis.
Oncotarget - 26 Jul 2016
Das Swadesh K, Guo Chunqing, Pradhan Anjan K, Bhoopathi Praveen, Talukdar Sarmistha, Shen Xue-Ning, Emdad Luni, Subler Mark A, Windle Jolene J, Sarkar Devanand, Wang Xiang-Yang, Fisher Paul B
Abstract excerpt
Cancer development and progression to metastasis is a complex process, which largely depends on bidirectional communication between tumor cells and their microenvironment. Melanoma differentiation associated gene-9 (mda-9, also known as Syntenin-1, SDCBP), a gene first cloned by our group, is robustly expressed in multiple cancers including melanoma and contributes to invasion and metastasis in a tumor...
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