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Article

Tetraspanin CD9 promotes the invasive phenotype of human fibrosarcoma cells via upregulation of matrix metalloproteinase-9.

PloS one - 1 Jan 2013

Herr Michael J, Kotha Jayaprakash, Hagedorn Nikolaus, Smith Blake, Jennings Lisa K

Abstract excerpt

Tumor cell metastasis, a process which increases the morbidity and mortality of cancer patients, is highly dependent upon matrix metalloproteinase (MMP) production. Small molecule inhibitors of MMPs have proven unsuccessful at reducing tumor cell invasion in vivo. Therefore, finding an alternativ...

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Identifiers

PMID: 23840773
DOI: 10.1371/journal.pone.0067766
PMCID: PMC3696041

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23840773-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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