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Article

Genetic predisposition to lung adenocarcinoma outcome is a feature already present in patients' noninvolved lung tissue.

Cancer science - 1 Jan 2023

Minnai Francesca, Noci Sara, Chierici Marco, Cotroneo Chiara Elisabetta, Bartolini Barbara, Incarbone Matteo, Tosi Davide, Mattioni Giovanni, Jurman Giuseppe, Dragani Tommaso A, Colombo Francesca

Abstract excerpt

Emerging evidence suggests that the prognosis of patients with lung adenocarcinoma can be determined from germline variants and transcript levels in nontumoral lung tissue. Gene expression data from noninvolved lung tissue of 483 lung adenocarcinoma patients were tested for correlation with overall survival using multivariable Cox proportional hazard and multivariate machine learning models. For genes whose...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 36114746
DOI: 10.1111/cas.15591
PMCID: PMC9807507

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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