Article
Genetic susceptibility variants for lung cancer: replication study and assessment as expression quantitative trait loci.
Scientific reports - 9 Feb 2017
Pintarelli Giulia, Cotroneo Chiara Elisabetta, Noci Sara, Dugo Matteo, Galvan Antonella, Delli Carpini Simona, Citterio Lorena, Manunta Paolo, Incarbone Matteo, Tosi Davide, Santambrogio Luigi, Dragani Tommaso A, Colombo Francesca
Abstract excerpt
Many single nucleotide polymorphisms (SNPs) have been associated with lung cancer but lack confirmation and functional characterization. We retested the association of 56 candidate SNPs with lung adenocarcinoma risk and overall survival in a cohort of 823 Italian patients and 779 healthy controls, and assessed their function as expression quantitative trait loci (eQTLs). In the replication study, eight SNPs...
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