Article
MiR-3130-5p is an intermediate modulator of 2q33 and influences the invasiveness of lung adenocarcinoma by targeting NDUFS1.
Cancer medicine - 1 Jun 2021
Zhan Juan, Sun Shenghua, Chen Yixing, Xu Chaoqun, Chen Qinwei, Li Minjie, Pei Yihua, Li Qiyuan
Abstract excerpt
Genome-wide association studies (GWAS) have reported a handful of loci associated with lung cancer risk, of which the pathogenic pathways are largely unknown. We performed cis-expression quantitative trait loci (eQTL) mapping for 376 lung cancer related GWAS loci in 227 TCGA lung adenocarcinoma (LUAD) and reported two risk loci as eQTL of miRNA. Among the miRNAs in association with lung cancer risk, we further...
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