Article
A Novel Genetic Variant in Long Non-coding RNA Gene NEXN-AS1 is Associated with Risk of Lung Cancer.
Scientific reports - 7 Oct 2016
Yuan Hua, Liu Hongliang, Liu Zhensheng, Owzar Kouros, Han Younghun, Su Li, Wei Yongyue, Hung Rayjean J, McLaughlin John, Brhane Yonathan, Brennan Paul, Bickeboeller Heike, Rosenberger Albert, Houlston Richard S, Caporaso Neil, Landi Maria Teresa, Heinrich Joachim, Risch Angela, Christiani David C, Gümüş Zeynep H, Klein Robert J, Amos Christopher I, Wei Qingyi
Abstract excerpt
Lung cancer etiology is multifactorial, and growing evidence has indicated that long non-coding RNAs (lncRNAs) are important players in lung carcinogenesis. We performed a large-scale meta-analysis of 690,564 SNPs in 15,531 autosomal lncRNAs by using datasets from six previously published genome-wide association studies (GWASs) from the Transdisciplinary Research in Cancer of the Lung (TRICL) consortium in...
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