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Article

Thymic epithelial tumors: examining the GTF2I mutation and developing a novel prognostic signature with LncRNA pairs to predict tumor recurrence.

BMC genomics - 16 Sept 2022

Liu Wei, Yang Hao-Shuai, Zheng Shao-Yi, Weng Jian-Hao, Luo Hong-He, Lei Yi-Yan, Feng Yan-Fen

Abstract excerpt

BACKGROUND: General transcription factor IIi (GTF2I) mutations are very common in thymic epithelial tumors (TETs) and are related to a more favorable prognosis in TET patients. However, limited research has been conducted on the role of GTF2I in the tumor immune microenvironment (TIME). Further, long non-coding RNAs (lncRNAs) have been associated with the survival of patients with TETs. Therefore, this study...

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Share to Gene Expression Regulation, Neoplastic
Share to Neoplasm Recurrence, Local

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasms, Glandular and Epithelial

Share to Prognosis

Share to RNA, Long Noncoding

Share to Thymus Neoplasms

Share to Transcription Factors, TFII

Share to Tumor Microenvironment

Source

Open in PubMed Open full text

Identifiers

PMID: 36114454
DOI: 10.1186/s12864-022-08880-3
PMCID: PMC9482307

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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