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GTF2I mutation frequently occurs in more indolent thymic epithelial tumors and predicts better prognosis.

Lung cancer (Amsterdam, Netherlands) - 1 Aug 2017

Feng Yanfen, Lei Yiyan, Wu Xiaoyan, Huang Yuhua, Rao Huilan, Zhang Yu, Wang Fang

Abstract excerpt

OBJECTIVES: A missense mutation in GTF2I was previously identified in thymic epithelioid tumor (TET). However, the clinicopathological relevance of GTF2I mutation has not been illustrated. We studied the prognostic importance of GTF2I mutation as well as its relation to histological subtypes in a large number of TETs. METHODS: TET samples from 296 patients with clinical and follow-up data were collected, and...

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PMID: 28676218
DOI: 10.1016/j.lungcan.2017.05.020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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