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Article

Significance of tumor mutation burden and immune infiltration in thymic epithelial tumors.

Thoracic cancer - 1 Jul 2021

Wang Zi-Ming, Xu Qi-Rong, Kaul David, Ismail Mahmoud, Badakhshi Harun

Abstract excerpt

BACKGROUND: Thymic epithelial tumors (TETs) are relatively rare malignant thoracic tumors. Tumor mutation burden (TMB) and immune infiltration play important roles in tumorigenesis. METHODS: Research data was obtained using the Cancer Genome Atlas (TCGA) database to evaluate the landscape of tumor mutations, related factors, and relationship of prognosis. The CIBERSORT algorithm was used to evaluate immune cell...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34033229
DOI: 10.1111/1759-7714.14002
PMCID: PMC8258363

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