Article
Genomic Analysis of Thymic Epithelial Tumors Identifies Novel Subtypes Associated with Distinct Clinical Features.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Aug 2017
Lee Hyun-Sung, Jang Hee-Jin, Shah Rohan, Yoon David, Hamaji Masatsugu, Wald Ori, Lee Ju-Seog, Sugarbaker David J, Burt Bryan M
Abstract excerpt
Purpose: To reconcile the heterogeneity of thymic epithelial tumors (TET) and gain deeper understanding of the molecular determinants of TETs, we set out to establish a clinically relevant molecular classification system for these tumors.Experimental Design: Molecular subgrouping of TETs was performed in 120 patients from The Cancer Genome Atlas using a multidimensional approach incorporating analyses of DNA...
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