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Article

Complement factor H variants are associated with microangiopathy lesions in IgA nephropathy.

International immunopharmacology - 1 Nov 2022

Hou Wanyin, Shi Sufang, Zhou Xujie, Wang Suxia, Cai Qingqing, Chen Pei, Liu Lijun, Zhu Li, Lv Jicheng, Zhang Hong

Abstract excerpt

BACKGROUND: Thrombotic microangiopathy (TMA) occurs in immunoglobulin A nephropathy (IgAN), and the pathogenesis is not known behind the endothelium injury. The genetic studies have indicated that complement factor H (CFH) and complement factor H-related protein genes (CFHRs)play a key role in IgAN. We perform a study to investigate the CFH /CFHRs gene variants and their roles in IgAN with microangiopathy based...

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Identifiers

PMID: 36113314
DOI: 10.1016/j.intimp.2022.109234

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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