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Article

Case Report: Severe Complement-Mediated Thrombotic Microangiopathy in IgG4-Related Disease Secondary to Anti-Factor H IgG4 Autoantibodies.

Frontiers in immunology - 1 Jan 2020

Breville Gautier, Zamberg Ido, Sadallah Salima, Stephan Caroline, Ponte Belen, Seebach Jörg D

Abstract excerpt

Objective: To first describe and estimate the potential pathogenic role of Ig4 autoantibodies in complement-mediated thrombotic microangiopathy (TMA) in a patient with IgG4-related disease (IgG4-RD). Methods: This study is a case report presenting a retrospective review of the patient's medical chart. Plasma complement C3 and C4 levels, immunoglobulin isotypes and subclasses were determined by nephelometry, the...

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Source

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Identifiers

PMID: 33643292
DOI: 10.3389/fimmu.2020.604759
PMCID: PMC7905310

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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