Article
Identification of genetic loci shared between Alzheimer's disease and hypertension.
Molecular genetics and genomics : MGG - 1 Nov 2022
Sullivan Megan, Deng Hong-Wen, Greenbaum Jonathan
Abstract excerpt
Alzheimer's disease (AD) and high blood pressure (BP) are prevalent age-related diseases with significant unexplained heritability. A thorough analysis of genetic pleiotropy between AD and BP will lay a foundation for the study of the associated molecular mechanisms, leading to a better understanding of the development of each phenotype. We used the conditional false discovery rate (cFDR) method to identify novel...
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