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Article

Genetic heterogeneity of Alzheimer’s disease in subjects with and without hypertension

1 Apr 2019

Abstract excerpt

Alzheimer's disease (AD) is a progressive neurodegenerative disorder caused by the interplay of multiple genetic and non-genetic factors. Hypertension is one of the AD risk factors that has been linked to underlying pathological changes like senile plaques and neurofibrillary tangles formation as well as hippocampal atrophy. In this study, we investigated the differences in the genetic architecture of AD between...

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PMID: 31055733
DOI: 10.1007/s11357-019-00071-5

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