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Article

Quantification of spatial subclonal interactions enhancing the invasive phenotype of pediatric glioma.

Cell reports - 30 Aug 2022

Tari Haider, Kessler Ketty, Trahearn Nick, Werner Benjamin, Vinci Maria, Jones Chris, Sottoriva Andrea

Abstract excerpt

Diffuse midline gliomas (DMGs) are highly aggressive, incurable childhood brain tumors. They present a clinical challenge due to many factors, including heterogeneity and diffuse infiltration, complicating disease management. Recent studies have described the existence of subclonal populations that may co-operate to drive pro-tumorigenic processes such as cellular invasion. However, a precise quantification of...

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Identifiers

PMID: 36044867
DOI: 10.1016/j.celrep.2022.111283
PMCID: PMC9449134

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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